If you or someone you love is struggling with fentanyl use, safe medical care can make all the difference. At Sheridan Grove Recovery, we provide 24/7 medically supervised fentanyl detox in Aurora, Colorado, serving people across the Denver metro area.

Fentanyl withdrawal can begin quickly and become intense within hours. Our licensed Aurora detox center offers around-the-clock monitoring, medication support, and compassionate clinical care to help you stabilize safely. After detox, we guide you into the next stage of treatment.

You don’t need to do it alone. We’re here to help 24/7.

What is fentanyl?

Fentanyl is a highly potent synthetic opioid. Doctors sometimes prescribe fentanyl for severe pain—often after surgery or for advanced cancer—but it remains addictive.  

Illicit versions of fentanyl can be 50 times stronger than heroin and 100 times more potent than morphine. More recently, illicit fentanyl drove a nationwide surge in overdose deaths. It's sometimes mixed into other drugs, like heroin, counterfeit prescription pills, or even methamphetamine. Since it's so potent, it can lead to overdose, even among people with high tolerance. 

Just how dangerous is fentanyl? 

In 2023, fentanyl and other opioids were involved in about 70% of all U.S. overdose deaths. Data from early 2024 showed a glimmer of hope: a sharp drop in fentanyl-related deaths. Still, the risk remains high, particularly in communities where street fentanyl is readily available, and the potency of a single dose can be unpredictable.

Overdose after relapse

Because fentanyl is so potent, the risk of overdose is present even for people who believe they "know their limit." A single lapse after a period of abstinence can become fatal due to lost tolerance. This makes relapse one of the most dangerous moments in the recovery process.

Co-occurring mental health

Fentanyl use is also closely linked to co-occurring mental health conditions such as depression, anxiety, PTSD, and trauma-related disorders. Many people use opioids to numb emotional pain, which can intensify withdrawal symptoms and increase relapse risk without professional support. Integrated detox and mental health screening are critical for long-term stability.

If you or your loved one is at risk, acting quickly can save a life.

You don’t need to do it alone. We’re here to help 24/7.

Fentanyl withdrawal symptoms & timeline

Once someone stops using fentanyl, they'll experience withdrawal symptoms. Their symptom severity will depend on how long they've used and how high their tolerance is.

Opioid withdrawal symptoms fall into two categories:

Physical symptoms

Mental & emotional symptoms

Severe muscle, joint, and bone pain

Anxiety and agitation

Nausea, vomiting, diarrhea

Depression or deep sadness

Sweating, chills, goosebumps

Intense cravings

Headaches and fatigue

Restlessness

Dilated pupils

Insomnia

Elevated heart rate or blood pressure

Brain fog and difficulty concentrating

Fentanyl withdrawal symptoms set in more quickly and are more severe than those of other opioids, like heroin. Without 24/7 support during detox, it can be easy to relapse. 

Medical detox timeline: What to expect

At our licensed drug detox facility in Colorado, clients receive 24/7 medical monitoring, comfort medications, hydration support, and sleep stabilization. When clinically appropriate, medication-assisted treatment (MAT) may begin during detox.

Short-acting opioids, like fentanyl, usually take a week to 10 days to fully clear from the body. For many people, symptoms usually come in a couple of waves.

Early withdrawal (8–24 Hours)

The first day after stopping fentanyl use brings on flu-like symptoms, like runny nose and eyes. Sweating, yawning, and sleep loss are also normal. Joint, muscle, and headaches also usually set in quickly. Cravings also start early.

Full withdrawal (24–72 Hours)

Symptoms peak within the first three days for most people detoxing from fentanyl. Blood pressure and heart rate usually rise. Some people feel agitated and even get a fever. Nausea, diarrhea, and vomiting make it hard to eat or drink, which can cause dehydration. For some, blood pressure can drop. 

The first month

People who had a severe addiction to fentanyl can experience discomfort for a few weeks. As time goes by, physical symptoms become less intense, which makes cravings—which also diminish—easier to cope with.

Post-acute withdrawal syndrome (PAWS)

Some people experience PAWS, though not everyone does. PAWS symptoms can last for a few months as the brain and body adjust to life without opioids. It usually involves less intense but persistent symptoms like: 

  • Mood instability 
  • Difficulty with memory or focus 
  • Sleep disturbances 
  • Periodic cravings 
  • Increased stress sensitivity 

PAWS is a significant factor in relapse—ongoing therapy and participation in support groups can help manage this stage.

Medically supervised fentanyl detox methods

A medical detox for fentanyl provides safety, comfort, and structure during withdrawal. Because fentanyl acts quickly and powerfully, professional monitoring reduces complications and relapse risk.

Inpatient detox programs

Our inpatient detox program in Aurora provides:

  • 24/7 medical oversight: Nurses and doctors are always on-site, able to immediately address severe symptoms like dehydration or cardiac changes. 
  • Structured routines: Daily schedules include medication times, meals, hydration schedules, periodic health checks, and support groups. 
  • Therapeutic activities: Evidence-based methods are available to process trauma, identify triggers, and prevent relapse. 
  • Dual diagnosis screening: Assessments to identify any co-occurring mental health conditions, which contribute to addictive behaviors. 
  • Transition planning: As symptoms subside, a counselor helps identify the next steps, whether that’s inpatient rehab, intensive outpatient care, or another type of treatment. 
  • Medications for opioid use disorder (MOUDs): FDA-approved medications like Subutex, methadone, and Suboxone can help manage cravings, making it easier to focus on recovery

After detox, many clients transition directly into our inpatient addiction treatment program for continued stabilization.

Medication-assisted treatment for fentanyl addiction

MAT, or medication-assisted treatment, greatly reduces cravings for fentanyl. When someone has fewer cravings, they're less likely to relapse during detox. Medication-assisted treatment is not just replacing one addiction with another; it's a controlled, therapeutic, tapered approach to withdrawal management.

Common medications used

MAT is a standard opioid use disorder treatment, especially for fentanyl addiction. It blends medication to control withdrawal and cravings with therapy and educational support for a holistic approach. 

Medications include: 

  • Buprenorphine: Reduces withdrawal symptoms and blocks the “high” from other opioids.  
  • Methadone: Replaces illicit opioids with a safe, regulated dose administered in a clinic. Daily administration and the clinic structure help taper the dose down over time. 
  • Buprenorphine/naloxone (Suboxone): Buprenorphine reduces withdrawal symptoms, and naloxone blocks the effects of other opioids if used. 

Benefits of medication-assisted treatment

  • Improved retention: Staying on an MAT plan lowers overdose and all-cause mortality risk. 
  • Craving control: Medication reduces physical discomfort and suppresses cravings, allowing individuals to focus on therapy and life rebuilding. 
  • Support for recovery: MAT is most effective when paired with counseling, life skills coaching, housing assistance, and employment support. States with broad MAT access and naloxone distribution have seen the largest drops in fentanyl-related deaths. 

At Sheridan Grove Recovery, MAT plans are carefully created, monitored, and adjusted by medical professionals. Our clinicians work with you to develop a personalized plan—adjusting medications to fit both your withdrawal experience and long-term goals.

Managing withdrawal and preventing relapse

Withdrawal management takes more than just medication and medical monitoring. When you stop using fentanyl, your brain and body take time to adjust. You'll need to learn new habits and coping skills to avoid relapse.

Withdrawal management strategies 

During detox, your comfort and safety are our top priorities. We use a comprehensive strategy to help you manage all your symptoms: 

  • Hydration: Nurses monitor your fluid intake and provide electrolyte drinks to combat dehydration—a major risk during withdrawal. 
  • Nutrition: Our kitchen serves small, protein- and vitamin-rich meals. We offer food that's easy on the stomach to minimize nausea and provide needed energy.
  • Movement and rest: Gentle movement (like short walks) helps reduce muscle pain, while rest is encouraged to allow your body to fully heal. 
  • Comfort measures: Warm showers, relaxation and grounding techniques, and breathwork help manage stress and agitation. 
  • Sleep support: Non-habit-forming sleep aids, a quiet environment, and sleep hygiene routines help restore sleep patterns disrupted by withdrawal.

Relapse prevention techniques 

Relapse prevention begins in detox and remains crucial long after withdrawal subsides. Personalized relapse prevention plans at Sheridan Grove Recovery include: 

  • Trigger identification: You’ll work with clinicians to recognize situations, people, or emotions that could spark cravings. Proactive planning helps you harness avoidance or coping strategies.
  • Coping skills: Practice deep breathing, mindfulness, journaling, or creative expression as outlets for stress and anxiety. 
  • Peer support: Early participation in support groups and regular check-ins with counselors reinforce positive changes and provide a sounding board for difficult moments. 
  • Emergency plans: Together, we develop crisis plans including trusted contacts, emergency phone numbers, and safe spaces in case of strong urges to use.

Comprehensive fentanyl addiction treatment 

Fentanyl detox isn't the last step in recovery. Comprehensive treatment helps support every part of your life after addiction.

Harm reduction approaches

Not everyone is ready for complete abstinence immediately, and harm reduction can be a life-saving bridge to recovery. For those not ready to enter treatment, Colorado provides harm reduction services like: 

Syringe access programs: Safe syringe exchange reduces the risk of HIV, hepatitis, and soft tissue infections

Dual diagnosis and co-occurring disorders

Many people living with fentanyl addiction also experience depression, anxiety, trauma, or PTSD. Treating these co-occurring disorders alongside addiction is crucial. 

  • Integrated care: Mental health professionals and addiction specialists collaborate for assessment, diagnosis, and joint treatment planning. 
  • Evidence-based therapies: Options include cognitive behavioral therapy (CBT), dialectical behavior therapy (DBT), trauma-informed care, and medication management as needed.

Substance abuse counseling and support groups

Clients are encouraged to participate in a mix of counseling and peer support: 

  • Individual therapy: Sets goals, builds trust, processes trauma, and develops personalized recovery strategies. 
  • Group therapy: Provides a sense of belonging, reduces isolation, and enhances communication skills. 
  • Community support groups: Resources like Narcotics Anonymous (NA), SMART Recovery, and faith-based recovery groups are available to sustain healing beyond treatment. 

Overdose prevention and naloxone use

How to respond to an overdose: 

  1. Call 911 immediately. Most states, including Colorado, have “Good Samaritan” laws to protect you and the victim from prosecution for seeking help. 
  2. Administer naloxone (Narcan). Use a Narcan kit (usually a nasal spray) according to the directions on the box. 
  3. Perform rescue breathing if the person is not breathing or only gasping, aiming for 1 breath every five to six seconds. 
  4. Place them in the recovery position (on their side) once they start breathing, and stay with them until help arrives. 

Prevention tips: 

  • Carry naloxone: Many states require pharmacies to stock it with little or no co-pay, especially under Medicaid. 
  • Don’t use alone: Encourage “never use alone” practices; hotlines and check-ins can save lives. 
  • Test your supply: Fentanyl test strips can detect contamination and help people who use drugs make safer choices.

Start fentanyl detox near Denver today

If you’re searching for a detox center near Aurora or Denver, Sheridan Grove Recovery offers 24/7 intake support and often same-day admissions.

Our admissions process is simple:

  1. Call our team anytime
  2. Verify Medicaid or insurance benefits
  3. Complete a brief assessment
  4. Arrive for admission, often the same day

Taking the first step can feel overwhelming—but help is available right now.

Reach out to Sheridan Grove Recovery for immediate help

Our team is standing by 24/7 to help you or a loved one stop using fentanyl. We accept Medicaid and many commercial insurance plans to make addiction treatment more accessible to everyone who needs it. Have questions? Reach out to us by calling 303.268.2987 or contacting us online.

Fentanyl detox FAQs

Generally, physical symptoms may start within 12 hours of the last dose and peak within 1–3 days. Psychological symptoms may continue for weeks or even months after stopping use. Seek professional help to manage withdrawal symptoms and prevent relapse.

It is not recommended to detox from fentanyl without medical supervision. Withdrawal from fentanyl can be dangerous and potentially life-threatening due to the risk of relapse and certain physical symptoms.

Traces of fentanyl can still be detected in urine and blood tests for up to 48–72 hours after use. It may take longer for people who've used it for a long time to completely eliminate fentanyl from their bodies.

Supporting a loved one during fentanyl detox can be challenging, but it is important to show compassion and understanding. Offer emotional support, assist in finding professional help, and encourage healthy habits such as exercise and proper nutrition. Most importantly, avoid enabling behavior that keeps them using.

Buprenorphine, methadone, naloxone, and naloxone/buprenorphine are all used to treat fentanyl withdrawal symptoms. These medications help ease the physical and psychological discomfort associated with detoxing from fentanyl.

Yes, there are harm reduction resources available in Denver for individuals struggling with fentanyl addiction. Syringe exchange programs, Narcan distribution, fentanyl test strips, and support groups are all available.

Trevor Collins

Chief Executive Officer

Trevor Collins serves as Chief Executive Officer of Sheridan Grove Recovery, where he is deeply committed to ensuring that every individual who enters treatment is met with dignity, compassion, and the support needed for lasting recovery. With more than 20 years of executive leadership experience in healthcare and behavioral health, Trevor leads with a patient-first philosophy that places clinical quality, safety, and outcomes at the center of every decision.

At Sheridan Grove Recovery, Trevor focuses on creating an environment where patients feel heard, respected, and empowered throughout their recovery journey. Under his leadership, the organization has strengthened care coordination, improved access to clinical and support services, and enhanced patient engagement and satisfaction—while also ensuring the operational and financial stability necessary to sustain high-quality care.

Trevor’s background spans substance use treatment, behavioral health, hospital operations, and value-based care models. He brings a thoughtful, systems-based approach to leadership, emphasizing evidence-based practices, strong interdisciplinary collaboration, and continuous improvement in both patient outcomes and staff support. He believes that when teams are well-supported and aligned around a shared mission, patients receive better care.

Guided by a strong sense of purpose, Trevor is dedicated to building programs that not only help individuals achieve sobriety, but also support long-term healing, resilience, and reintegration into their families and communities. He holds a Master of Business Administration from Western Governors University and a Bachelor of Science in Applied Social Science and Organizational Leadership from Colorado State University–Global Campus.